All the patients received cranial radiation (range: 12–60 Gy). The primary diseases included 2 germinoma, 2 acute lymphoblastic lymphoma, 2 medulloblastoma, 1 diffuse astrocytoma, 1 pilocytic astrocytoma, 1 pituitary adenoma and 1 metastatic tumor from lung cancer. There was no sex predominance (M: 5, F: 5), and the median age of the primary diseased was 13.5 years (range: 1–39). Between 20, we identified 10 patients with RIG, which satisfied the Cahan’s criteria in our data base. The purpose of this study is to understand the clinical characteristics and outcome of patients with radiation-induced glioma (RIG). The development of gliomas subsequent to therapeutic cranial irradiation is a rare but serious complication.
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